Although passengers frequently inquire things to do in amarillo tx. At the halfway point on the storied US Route 66, is Amarillo. Driving through the city's Historic Route 66 District will give you a sense of what it might have been like to pass through this area in the middle of the 20th century. The Quarter Horse Museum and the Panhandle Plains History Museum are just two of the many distinctive museums in Amarillo dedicated to the history and culture of West Texas. One of the most well-liked destinations in Amarillo is Cadillac Ranch, where you may venture outside of the city to practise your graffiti skills. Or, hike the trails in the close-by Palo Duro Canyon to take in some of the state's breathtaking landscapes.